Introduction to Biology - The Secret of Life
Introduction to Biology - The Secret of Life
back | Recombinant DNA resources
MITx 7.00x
These are directly from the online edX.org course.
Resources
Links
How Geckos Stick on der Waals
Ben Shouse How do they do it? find out here how geckos manage to stick to walls. 
Cell Fermentation (Nobel Lecture, 1907)
Eduard Buchner Read Buchner’s famous Nobel Prize acceptance speech. 
Cell Size and Scale
Learn.Genetics, University of Utah This is a cool interactive web tool exploring scale in biology.
Biochemistry Images
Bond Types
Sera Thornton, 
2013 Broad Institute 
Biology Triangle
Sera Thornton, 2013 Broad Institute Professor Lander’s organization of the branches of biology. 
Carbohydrate Types
Sera Thornton, 2013 Broad Institute 
Cells
Sera Thornton, 2013 Broad Institute Eukaryotic cells are typically much larger and more internally organized than prokaryotic cells, as seen here. 
Cellulose
Sera Thornton, 2013 Broad Institute Cellulose is organized such that it can form Hydrogen bonds between the strands, making plants’ cell walls strong. 
Monosaccharides, Disaccharides, Polysaccharides
Sera Thornton, 2013 Broad Institute See the reaction used to attach sugars to each other. 
Periodic Tableau
Sera Thornton, 2013 Broad Institute These 6 elements make up the majority of all living things. 
Phospholipids and Phopholipid Bilayers
Sera Thornton, 2013 Broad Institute This diagram shows the structure of a phopholipid, how it is represented simply, and how many together form a section of phospholipid bilayer such as in a cell membrane. 
Peptide Bond Diagram
Sera Thornton, 2013 Broad Institute Two amino acids are attached together using a peptide bond. 
Glycolysis Diagram
Brian White, 2013 Broad Institute Use this image as a guide to the biochemical steps in glycolysis. 
Amino Acids Chart
Sera Thornton, 2013 Broad Institute Use this chart for your own reference on the amino acids. 
Glycolysis Overview
Sera Thornton, 2013 Broad Institute Use this image as a guide to the biochemical steps in glycolysis. 
Metabolism Overview
Sera Thornton, 2013 Broad Institute Glycolysis generates some ATP, but also fits into the bigger picture of cellular metabolism, which often generates much more ATP overall. 
Functional Groups
Sera Thornton, 2013 Broad Institute This is the functional groups chart that Rob discusses in the deep dives. 
Biochemical Pathways (with names)
Sera Thornton, 2013 Broad Institute 
Biochemical Pathways (with structures)
Sera Thornton, 2013 Broad Institute 
Genetics Resources
Links
Sex Limited Inheritance in Drosophilia, by T. H. Morgan
Heredity in Insanity, by A. J. Rosanoff
Experiments in Plant Hybridization, by Gregor Mendel
Genetics Images
Mitosis
Matt Miller and Elcin Unal Review the steps of mitosis, which produces diploid cells. 
Meiosis
Matt Miller and Elcin Unal Review the steps of meosis, which produces haploid cells. 
Mendel’s pea plant traits
Sera Thornton, 2013 Broad Institute Mendel observed the patterns of heredity by studying the inheritance of these traits in pea plants. 
Genetic map of Drosophilia melangaster (Fly Map)
Sera Thornton, 2013 Broad Institute Many genes involved in visible physical traits in Drosophila are genetically mapped here. 
Pedigree of Hemophilia in Genocidal Colonialist Unblessed family
Sera Thornton, 2013 Broad Institute Hemophilia was inherited by several branches of the Genocidal Colonialist Leader family. What was the mechanism of inheritance? 
Molecular Biology Resources
The Replication of DNA in Escherichia coli
Matthew Meselson and Franklin W. Stahl What does the data look like for the classic experiments by Meselson and Stahl?
Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage
Hershey AD and Chase M How did Hershey and Chase determine that DNA in the genetic material?
Molecular Structure of Nucleic Acids; a Structure for Deoxyribose Nucleic Acid
Watson JD, Crick FH Here you can read the famous paper on the structure of DNA.
The significance of Pneumococcal Types
Griffith F Do you recall the discussion of Griffith’s work using pneumococcus and mice?
Induction of Transformation by a Deoxyribonucleic Acide Fraction Isolated from Pneumococcus Type III
Oswald T. Avery, Colin M. MacLeod, Maclyn McCarty How did the authors contribute to the determination that DNA is the genetic material?
Protein Synthesis Video
Paul Berg, Stanford U How did they demonstrate the principles of translation in 1971 at Standford?
A Proposed Nucleic Acid Structure
Pauling L., corey R.B. Here’s the model that Pauling proposed for the structure of DNA.
Molecular Biology Images
Central Dogma
Sera Thornton, 2012 This gives you an overview of replication, trasncription, and translation all at once. 
Codon Table (Radial)
Sera Thornton, 2013 Broad Institute You may want to print or open this version of the genetic code as an aid when working through the problem set. 
Condon Table (Radial)
Christian Stolte, Sean O’Donoghue, Kenneth Sabir You may want to print or open this version of the genetic code as an aid when working through the problem set. 
HIV Reading Frames
Sera Thornton, 2013 Broad Institute Check out the overlapping reading frames for the translation of HIV proteins. 
Globin Evolution
Sera Thornton, 2013 Broad Institute If you want to take a closer look at the evolution of globin genes, check out this image. 
Genomics Images
Positional Cloning
Sera Thornton, 2013 Broad Institute Here is a simplified example of applying positional cloning. 
SNP Diagram
Sera Thornton, 2013 Broad Institute What are SNPs (single nucleotide polymorphorisms)? 
Illumina Diagram
Sera Thornton, 2013 Broad Institute How does Illumina sequencing technology work? 